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  • New in Clinical Guidance | ACC AHA ACS Guideline, More
    Dual antiplatelet therapy (DAPT) with aspirin and an oral P2Y12 inhibitor is indicated for at least 12 months as the default strategy in patients with ACS who are not at high bleeding risk, while several strategies are recommended for patients with a higher bleeding risk
  • 2025 Guideline for Acute Coronary Syndromes - Professional Heart Daily
    Dual antiplatelet therapy is recommended in ACS patients Ticagrelor or prasugrel is recommended in preference to clopidogrel in NSTE-ACS and STEMI patients undergoing PCI
  • ACC AHA Task Force on Clinical Practice Guidelines
    Several strategies are available to reduce bleeding risk in patients with ACS who have undergone PCI and require antiplatelet therapy: (a) in patients at risk for gastrointestinal bleeding, a proton pump inhibitor is recommended; (b) in patients who have tolerated dual antiplatelet therapy with ticagrelor, transition to ticagrelor monotherapy
  • ACC, AHA Issue New Acute Coronary Syndromes Guideline
    Dual antiplatelet therapy (DAPT), comprising aspirin plus a P2Y12 inhibitor, is already recommended for people with ACS While it reduces the risk of recurrent MI, it can increase bleeding risk in some patients
  • Antiplatelets for the Prevention of Occlusive Vascular Events
    • Patients who require ‘dual antiplatelet therapy’ (e g , clopidogrel and aspirin) post MI who were previously taking clopidogrel for Stroke TIA PAD should continue with clopidogrel monotherapy after 12 months of dual antiplatelet therapy
  • New Guideline on Acute Coronary Syndromes: Key Takeaways
    The recommendations for dual antiplatelet therapy (DAPT) are similar to the 2021 revascularization guideline, but now with additional strategies to consider for patients with high risk of bleeding or for reducing bleeding risk after treatment for MI
  • 2025 ACC AHA ACEP NAEMSP SCAI Guideline for the Management of Patients . . .
    undergone PCI and require antiplatelet therapy: (a) in patients at risk for gastrointestinal bleeding, a proton pump inhibitor is recommended; (b) in patients who have tolerated dual antiplatelet therapy with tica-grelor, transition to ticagrelor monotherapy is recommended $1 month after PCI; or (c) in patients
  • New: Focused Update of the Guidelines for the Use of Antiplatelet Therapy
    Use and duration of dual antiplatelet therapy in acute coronary syndromes and elective PCI with potent DAPT (P2Y12 inhibitor) choice in patients who present with an acute coronary syndrome (ACS), possible DAPT de-escalation strategies after PCI, and shortened DAPT in high bleeding risk patients
  • New Recommendations for Antithrombotic Therapy in Patients with Acute . . .
    Administer dual antiplatelet therapy (DAPT) for 12 months, unless there is high bleeding risk, in which case consider de-escalation to ticagrelor monotherapy (class 1) or clopidogrel monotherapy (class 2b) after 1 month Consider anticoagulation in all patients prior to PCI (class 1)
  • Dual antiplatelet therapy for the general cardiologist: recent evidence . . .
    Dual antiplatelet therapy (DAPT) is the mainstay treatment following percutaneous coronary intervention (PCI) with drug-eluting stents (DES) to reduce stent thrombosis and target lesion failure However, this benefit is intrinsically associated with an increased risk of bleeding





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