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diethylstilbestrol    

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  • Diethylstilbestrol - Wikipedia
    Diethylstilbestrol (DES), also known as stilbestrol or stilboestrol, is a nonsteroidal estrogen medication [5][6][7] Its use now rare; in the past, it was widely used for a variety of indications, including pregnancy support for those with a history of recurrent miscarriage, hormone therapy for menopausal symptoms and estrogen deficiency
  • Diethylstilbestrol (DES) Exposure and Cancer - NCI
    A fact sheet about the drug DES (diethylstilbestrol), a synthetic form of estrogen, and the health issues, including cancer risks, of people prenatally exposed to it
  • DES Exposure: Questions and Answers - American Cancer Society
    DES (diethylstilbestrol) is a man-made (synthetic) form of the hormone estrogen Doctors prescribed DES from 1940 until 1971 to help some pregnant women avoid problems with pregnancy Though it was found to be ineffective, it was given to millions of women in the United States during this time
  • Diethylstilbestrol: Indications, Side Effects, Warnings . . .
    Easy-to-read patient leaflet for Diethylstilbestrol Includes indications, proper use, special instructions, precautions, and possible side effects
  • Outcome and follow-up of diethylstilbestrol (DES) exposed . . .
    Diethylstilbestrol (DES) is a nonsteroidal estrogen first synthesized in 1938 It was initially used for postpartum lactation suppression and treatment of postmenopausal symptoms but quickly became an accepted intervention for prevention of miscarriage, preterm delivery, and other obstetric problems
  • Diethylstilbestrol and its Multigenerational Effects - AWIS
    Diethylstilbestrol (DES) was once thought to be a “wonder drug” that reduced complications in pregnancy It is now known as an endocrine disruptor and exposure to it causes carcinogenic effects that can continue through several generations
  • Diethylstilbestrol - 15th Report on Carcinogens - NCBI Bookshelf
    The strongest evidence for carcinogenicity comes from epidemiological studies of women exposed to diethylstilbestrol in utero (“diethylstilbestrol daughters”), which found that diethylstilbestrol caused clear-cell adenocarcinoma, a rare cancer of the vagina and cervix
  • Diethylstilbestrol (DES) Exposure - OncoLink
    Diethylstilbestrol (DES) was the first synthetic (manmade) estrogen Estrogen is a type of hormone that is responsible for female sex characteristics It was given to pregnant females from 1938 to 1971 It was thought to prevent miscarriages and help healthy pregnancies
  • Diethylstilbestrol: Uses, Interactions, Mechanism of Action . . .
    According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), diethylstilbestrol has been listed as a known carcinogen (Merck, 11th ed) The FDA withdrew its approval for the use of all oral and parenteral drug products containing 25 milligrams or more of diethylstilbestrol per unit dose 6 Modality Small Molecule Groups Approved
  • How Diethylstilbestrol Exposure Can Affect Your Health - AARP
    What is diethylstilbestrol? DES was mainly intended to prevent preterm labor, miscarriage and other pregnancy complications, although it was also used to treat a variety of other conditions including vaginitis and menopause symptoms





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