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  • Clinical efficacy and mechanisms of biologics for chronic . . .
    outcomes of biologic therapy versus endoscopic sinus surgery, and discuss therapies in development and future directions (J Allergy Clin Immunol 2025;155:1401-10 ) Key words: Chronic rhinosinusitis, nasal polyp, CRSwNP, CRSsNP, biologic, benralizumab, dupilumab, mepolizumab, omalizumab, tezepelumab Chronic rhinosinusitis (CRS) encompasses a
  • Tezspire for Nasal Polyps: A New Targeted Therapy on the . . .
    June 17, 2025 Tezspire for Nasal Polyps: A New Targeted Therapy on the Horizon June 17, 2025 Anaphylm: The Needle-Free Epinephrine June 4, 2025 FDA Warning: Stopping Zyrtec or Xyzal May Cause Rebound Itching—What Allergy Patients Need to Know June 3, 2025 How the Palisades and Altadena Fires Are Affecting Your Sinuses, Lungs, and Long
  • Chinese Position Paper on Biologic Therapy for Chronic . . .
    Emerging biologics that selectively target key cytokines present a promising therapeutic alternative for patients suffering from severe, uncontrollable chronic rhinosinusitis with nasal polyps (CRSwNP) Despite the limited availability of registered biologics for CRSwNP treatment in China, the count …
  • Clinical efficacy and mechanisms of biologics for chronic . . .
    Tissue IgE levels positively correlate with the regrowth of nasal polyps, and sensitization to environmental aeroallergens can predict the need for repeat ESS 96 Treatment of CRSwNP with an anti-IgE biologic (omalizumab) resulted in a significant reduction in nasal polyp size as well as in symptom severity scores for patients both with and
  • Ultra-long-acting biological therapy for chronic . . . - The Lancet
    Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a common and particularly severe subset of sinonasal inflammatory disease that is characterised by benign outgrowths of the inflamed mucosa The management framework of CRSwNP substantially shifted with the introduction of biological agents 1–3 These therapies, targeting the Th2 cell cytokine pathways, drove reductions in both systemic





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