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  • Gentamicin - Wikipedia
    Gentamicin is a type of aminoglycoside [4] and works by disrupting the ability of the bacteria to make proteins, which typically kills the bacteria [4] Gentamicin is naturally produced by the bacterium Micromonospora purpurea, [8] [4] was patented in 1962, approved for medical use in 1964 [9]
  • History of Gentamicin - The Drug History Podcast
    Gentamicin is an aminoglycoside antibiotic that was first discovered in the late 1950s by scientists at the pharmaceutical company Schering Corporation (now part of Merck Co ) It was first approved for use in the United States in 1963 and has since become a widely used antibiotic for the treatment of a variety of bacterial
  • Gentamicin - StatPearls - NCBI Bookshelf
    Gentamicin is a widely used antibiotic, being an important part of the medical practice since the 1940s Although there is an increasing antimicrobial resistance rate, gentamicin is still a powerful option for many gram-negative infections, including severe ones
  • Gentamicin | C21H43N5O7 | CID 3467 - PubChem
    Gentamicin | C21H43N5O7 | CID 3467 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety hazards toxicity information, supplier lists, and more
  • Remembering Marvin Weinstein (1916–2011) | The Journal of Antibiotics
    Gentamicin, described in 1963, showed strong activity against a variety of microbes, including Pseudomonas aeruginosa and kanamycin- and neomycin-resistant bacteria Indeed, its spectrum of
  • Tutorial: ABC of Antimicrobials: Gentamicin - MICROBIOLOGY MATTERS
    ORIGINS: Gentamicin was discovered in 1963 by Weinstein and colleagues from the soil fungus Micromonospora purpura (of the Actinomycete group) Introduced commercially in 1969 MECHANISM OF ACTION: Gentamicin inhibits bacterial protein synthesis mainly through binding with the 30S ribosomal subunit, and acts through two different mechanisms In
  • Aminoglycosides: An Overview - PMC
    Although streptomycin has traditionally been the agent of choice for these infection types, gentamicin is now widely used because of the broader availability of this agent as well as data suggesting similar efficacy to streptomycin (Mwengee et al 2006; Snowden and Stovall 2011)
  • Update on new medicinal applications of gentamicin: evidence . . . - PubMed
    Gentamicin (GM) was discovered in 1963 and was introduced into parenteral usage in 1971 Since then, GM has been widely used in medicinal applications The Food and Drug Administration of the United States approved the routine prescription of GM to treat the following infectious disorders: infection …
  • Gentamicin - ScienceDirect
    Although the isolation of gentamicint was first reported in 1963,29 it was not until April 1969 that this antibiotic became available for commercial use in the United States
  • Gentamicin: Uses, Interactions, Mechanism of Action - DrugBank Online
    Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963 7 It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability 5,8 Gentamicin is effective against both gram-positive and gram-negative organisms but is particularly





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