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  • The cellular mechanisms of the antiemetic action of dexamethasone and . . .
    Dexamethasone, one of the glucocorticoids, has been suggested as a first-line drug for preventing low-level emetogenic chemotherapy- and radiotherapy-induced nausea and vomiting, and in patients with only one or two risks for postoperative nausea and vomiting (PONV)
  • The cellular mechanisms of the antiemetic action of dexamethasone and . . .
    Dexamethasone, one of the glucocorticoids, has been suggested as a first-line drug for preventing low-level emetogenic chemotherapy- and radiotherapy-induced nausea and vomiting, and in patients with only one or two risks for postoperative nausea and vomiting (PONV)
  • Antiemetic drugs: what to prescribe and when - PMC
    Dexamethasone Central inhibition of prostaglandin synthesis and encephalin release When combined with 5-HT3 antagonists there are reduced serotonin concentrations in the gut and increased sensitivity of 5-HT3 receptors to antiemetics
  • Dexamethasone - StatPearls - NCBI Bookshelf
    Summarize the mechanism of action of dexamethasone Describe the contraindications of dexamethasone Review the importance of improving care coordination among interprofessional team members to improve outcomes for patients where dexamethasone can play a role in diagnosis or treatment
  • Antiemetic activity of corticosteroids in patients receiving cancer . . .
    Dexamethasone has also been demonstrated to be effective as monotherapy for the management of CINV High-dose intravenous (i v ) dexamethasone reduced the risk for nausea and vomiting in patients receiving doxorubicin (a total of 22 cycles), but not for those being treated with combinations based
  • Antiemetics · Part One - LITFL
    Antiemetic drugs can be classified by their mechanism of action: Has additional effects on postsurgical pain and fatigue Nausea Ineffective for vomiting due to motion sickness or dopamine agonism Hepatic to inactive metabolites Dose reduction in hepatic impairment t 1 2 3 24 Peck TE, Hill SA
  • Routine use of dexamethasone for postoperative nausea and vomiting: the . . .
    Although the precise mechanism of action is not known, it has been suggested that the antiemetic effect could be due to the inhibition of prostaglandins, prevention of serotonin release in the gut, reduction in neural 5-hydroxytryptophan levels or release of endorphins 2
  • The cellular mechanisms of the antiemetic action of dexamethasone and . . .
    Dexamethasone, one of the glucocorticoids, has been suggested as a first-line drug for preventing low-level emetogenic chemotherapy-and radiotherapy-induced nausea and vomiting, and in patients with only one or two risks for postoperative nausea and vomiting (PONV)
  • Antiemetic Medications - StatPearls - NCBI Bookshelf
    Determine the mechanism of action of various antiemetic medications Assess the potential adverse events for various antiemetic medications Communicate the role of interprofessional coordination in guiding patient care when antiemetics are part of the patient's therapy to achieve optimal outcomes
  • The Pharmacological and Clinical Roles of Antiemetics: A Narrative . . .
    Dexamethasone, a glucocorticoid, has also been shown to have antiemetic properties Aprepitant (or its prodrug, fosaprepitant) exerts its effect by blocking neurokinin-1 (NK-1) neurokinin receptors [4]





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