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  • GitHub - saeyslab nichenetr: NicheNet: predict active ligand . . .
    nichenetr: the R implementation of the NicheNet method The goal of NicheNet is to study intercellular communication from a computational perspective NicheNet uses human or mouse gene expression data of interacting cells as input and combines this with a prior model that integrates existing knowledge on ligand-to-target signaling paths
  • GitHub - msraredon NICHES: Niche Interactions and Cellular . . .
    NICHES is a simple but powerful computational toolset to analyze cell-cell signaling at the single-cell level NICHES creates unique one-to-one pairs of cells and characterizes each cellular interaction across queried ligand-receptor signaling mechanisms This allows low-dimensional embedding of cellular interactions in signal-space
  • Welcome to NicheMapR - NicheMapR
    NicheMapR is a suite of programs for the R environment that compute fundamental physical and chemical constraints on living things It aims at asking the general question: Can an organism complete its life cycle in a particular place and time, without overheating, desiccating or starving?
  • nichenetr package - RDocumentation
    nichenetr: the R implementation of the NicheNet method The goal of NicheNet is to study intercellular communication from a computational perspective NicheNet uses human or mouse gene expression data of interacting cells as input and combines this with a prior model that integrates existing knowledge on ligand-to-target signaling paths
  • 单细胞分析之细胞交互-4：NicheNet - 简书
    一般的预测细胞交互的软件往往只考虑sender细胞的配体和receiver细胞的受体表达，但细胞交互过程除了配体-受体相互作用以外，还包含了receiver细胞接受信号后相关通路的激活。 NicheNet输入基因表达数据，并将其与通过整合信号通路而构建的模型相结合。 不止是预测配体与受体的相互作用，还整合了细胞内信号传导。 因此，NicheNet可以预测1)来自一或多种细胞中的配体（sender）影响了与之相互作用的细胞中哪些基因的表达和2)哪些靶基因受每种配体影响以及可能涉及哪些信号传导介质。 首先从公共数据库中收集配体-受体配对信息、信号通路、基因调控网络等信息，整合成配体主导的权重配体-靶基因调控模型。
  • Find the School that Fits You Best - Niche
    Finding the right school shouldn’t be hard From K‑12 to college to grad school, we make it easy to discover and connect with the best ones for you Get accepted without an application No application No waiting With Direct Admissions, colleges can accept you based on the information in your Niche Profile Your search is unique Just like you





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