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  • Practical Experiment 6: To synthesize and characterized 2,3 diphenyl . . .
    Isoquinoline derivatives have many pharmaceutical applications including use as antispasmodics, antitussives, anesthetics, and in the production of morphine and related alkaloids Isoquinoline can be prepared through the Bischler-Napieralski synthesis which involves the condensation and rearrangement of 2-phenylethylamine or through the
  • Recent Updates on the Synthesis of Bioactive Quinoxaline . . . - MDPI
    Potey et al described a new synthetic approach for the synthesis of libraries of quinoxaline sulfonamides and studied their antimicrobial activities The starting 2,3-diphenylquinoxaline (56) was prepared in an excellent yield by condensation of o-phenylenediamine (OPD) (34) and diketone 78
  • A Greener Chemistry Approach for Synthesis of 2,3-diphenyl . . . - IJISET
    The objective of present research work is to provide green technique for synthesis of 2,3-diphenyl quinoxaline Quinoxaline derivatives are well known in the pharmaceutical industry and have been shown to possess a broad spectrum of biological activities Highly efficient and simple methods have been described in this manuscript for the
  • Comprehensive Review on Versatile Pharmacology of Quinoxaline . . .
    Goyal Rakesh et al designed and synthesized a new series of 2,3-diphenylquinoxaline-7-sulphonyl chloride using an elimination-addition reaction In silico studies revealed a good binding affinity for the compounds towards gamma-glutamyl transpeptidase enzyme
  • Synthesis, Reactions and Biological Activity of Quinoxaline Derivatives
    Quinoxalines and fused ring systems show diverse pharmacological activities Syntheses of quinoxaline derivatives via many different methods of synthetic strategies have been presented Keywords: Quinoxalines, o -phenylenediamine, Oxidation, Nitration, Diazotization, Alkylation, Addition, Condensation, Cyclization, Substitutions reactions
  • International Journal of Biopharmaceutics
    Benzopyrazines a versatile heterocyclic scaffold in 2, 3-diphenyl quinoxaline plays a significant role in the pharmaceutical field and present in many medicinally important derivatives used as antiviral, anticancer, antimicrobial agents, etc
  • The design and synthesis of 2,3-diphenylquinoxaline amine derivatives . . .
    In this study, a series of bipolar, donor–acceptor–donor (D–A–D)-based quinoxaline diarylamine heterocyclic amine derivatives were synthesized in good yield by the Buchwald–Hartwig amination reaction and fully characterized by different spectroscopic methods
  • Research Journal of Pharmaceutical, Biological and Chemical
    The aim of the present study was to synthesize new compounds, 2,3-diphenyl,6-sub quinoxaline 1,4-di-N- oxide derivatives and to investigate the antimicrobial activities 6-sub, 2,3-diphenyl quinoxalines (III a–f) have been
  • ISSN: 2349-7092 Re view Article Quinoxaline Derivatives: Synthesis and . . .
    Quinoxaline derivatives are well known in the pharmaceutical industry and have been shown to possess a broad spectrum of biological activities including antimicrobial [7], antiviral [8], anti- inflammatory [9], anticancer [10], and kinase inhibitory activities
  • Synthesis and Characterization of 2,3-Diphenyl Quinoxaline 1,4-di-N . . .
    ABSTRACT The aim of the present study was to synthesize new compounds, 2,3-diphenyl,6-sub quinoxaline 1,4-di-N- oxide derivatives and to investigate the antimicrobial activities 6-sub, 2,3-diphenyl quinoxalines (III a–f) have been prepared by the condensation of substituted o-phenylene diamines (I) with benzil (II)





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